HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrahydrofurfurylamine → HCID 58548374, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrahydrofurfurylamine | HCID 253298 | — |
| Edukt | 3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-isonicotinic acid | HCID 70098928 | — |
| Produkt | HCID 58548374 | HCID 58548374 | 77% |
Reaktionsschritte
According to the procedure described in step 3 of example 99, 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-isonicotinic acid (example 99, step 2) was reacted with (tetrahydrofuran-2-yl)methanamine, providing the title compound as yellow solid (77%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08623866B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-f942ca0cd54a435bbd04ab545989cbff |
| Quellennotiz | uspto-grants-2014_01 |