HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluprostenol → HCID 178459549, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Fluprostenol | HCID 5311100 | — |
| Edukt | HCID 178418600 | HCID 178418600 | — |
| Lösungsmittel | Methanol--water (1/1) | HCID 22242641 | — |
| Produkt | HCID 178459549 | HCID 178459549 | — |
Reaktionsschritte
To travoprost free acid ((+)-fluprostenol free acid) 3 in MeOH/H2O was added L-Arginine (>98%) (Sigma-Aldrich Cat. A5006) and the solution was stirred for 30 minutes. The solvents were evaporated then azeotroped with Et2O and hexanes to give white crystalline travoprost-L-Arginine salt 4 (quantitative).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08623918B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-62aebbbdd09a41f4866fa8fbcec861cb |
| Quellennotiz | uspto-grants-2014_01 |