HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluprostenol → HCID 178459548, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Fluprostenol | HCID 5311100 | — |
| Edukt | HCID 178512822 | HCID 178512822 | — |
| Lösungsmittel | Methanol--water (1/1) | HCID 22242641 | — |
| Produkt | HCID 178459548 | HCID 178459548 | — |
Reaktionsschritte
To travoprost free acid ((+)-fluprostenol free acid) 3 in MeOH/H2O is added L-Homoarginine and the solution is stirred for 30 minutes. The solvents are evaporated then azeotroped with Et2O and hexanes to give white crystalline travoprost-L-Homoarginine salt 5 (quantitative).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08623918B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-329ac80dce504053b0ad51bc4eddee3d |
| Quellennotiz | uspto-grants-2014_01 |