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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 469559Erstellt: 24. Oktober 2026

Cyclopentylacetic acid → 2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamide

https://huagongshe.com/de/reaction/469559

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyclopentylacetic acidHCID 71606—
Edukt2-amino-4-(trifluoromethyl)phthalazin-1(2H)-oneHCID 67161111—
Produkt2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamideHCID 53238204—

Reaktionsschritte

The product of Example 11B and 2-cyclopentylacetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.56-11.57 (m, 1H), 8.43 (d, J=8.5 Hz, 1H), 8.11-8.17 (m, 1H), 8.04-8.08 (m, 1H), 8.00-8.05 (m, 1H), 2.34 (d, J=7.4 Hz, 2H), 2.16-2.28 (m, 1H), 1.77-1.86 (m, 2H), 1.57-1.66 (m, 2H), 1.48-1.57 (m, 2H), 1.21-1.32 (m, 2H); MS (ESI) m/z 340 (M+H)+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08629143B2
Quelldatensatzuspto-grants-2014_01
ORD IDord-8f9c274f0f4e41dd96ea0d065d4d016f
Quellennotizuspto-grants-2014_01