HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclopentylacetic acid → 2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclopentylacetic acid | HCID 71606 | — |
| Edukt | 2-amino-4-(trifluoromethyl)phthalazin-1(2H)-one | HCID 67161111 | — |
| Produkt | 2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamide | HCID 53238204 | — |
Reaktionsschritte
The product of Example 11B and 2-cyclopentylacetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.56-11.57 (m, 1H), 8.43 (d, J=8.5 Hz, 1H), 8.11-8.17 (m, 1H), 8.04-8.08 (m, 1H), 8.00-8.05 (m, 1H), 2.34 (d, J=7.4 Hz, 2H), 2.16-2.28 (m, 1H), 1.77-1.86 (m, 2H), 1.57-1.66 (m, 2H), 1.48-1.57 (m, 2H), 1.21-1.32 (m, 2H); MS (ESI) m/z 340 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08629143B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-8f9c274f0f4e41dd96ea0d065d4d016f |
| Quellennotiz | uspto-grants-2014_01 |