HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Aminopyridazine → 5-cyclohexyl-N-pyridazin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Aminopyridazine | HCID 298492 | — |
| Edukt | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Produkt | 5-cyclohexyl-N-pyridazin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide | HCID 71294298 | — |
Reaktionsschritte
This compound was prepared following the same procedure as described in Example 11 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 4b) (100 mg, 0.33 mmol) and 4-pyridazinamine (CAN 20744-39-2, 31.4 mg, 0.33 mmol) as starting materials; off white solid (60 mg, 47.8%). MS (ESI): 381.4 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08629166B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-63f01adf23b44b20887b196c114af723 |
| Quellennotiz | uspto-grants-2014_01 |