HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Chloroform → 4,4-Dimethyl-7-(2,4-dimethoxybenzoyl amino)-8-nitro-2H,4H-isoquinoline-1,3-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Chloroform | HCID 6212 | — |
| Edukt | 2,4-Dimethoxybenzoyl chloride | HCID 2734719 | — |
| Edukt | 1,3(2H,4H)-Isoquinolinedione, 7-amino-4,4-dimethyl-8-nitro- | HCID 11118443 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | 4,4-Dimethyl-7-(2,4-dimethoxybenzoyl amino)-8-nitro-2H,4H-isoquinoline-1,3-dione | HCID 20384991 | — |
Reaktionsschritte
2.7 gm of 4,4-dimethyl-7-amino-8-nitro-2H,4H-isoquinoline-1,3-dione were admixed with 50 ml of chloroform and 2.5 ml of triethylamine. Subsequently, 2.2 gm of 2,4-dimethoxybenzoylchloride were added, and the mixture was refluxed for 2 hours. After cooling the solution was evaporated and the precipitate was suction-filtered off and digested with water while heating.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04176184 |
| Quelldatensatz | uspto-grants-1979_11 |
| ORD ID | ord-4daf93f3d00e408d87d772158b269ff5 |
| Quellennotiz | uspto-grants-1979_11 |