HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → 5,7-Dichloro-4-(3,4-dimethoxyphenyl)-3-methyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | Methyl isoeugenol | HCID 7128 | — |
| Edukt | 3,5-Dichloroaniline | HCID 12281 | — |
| Edukt | 2-Ketobutyrate | HCID 3593277 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | 5,7-Dichloro-4-(3,4-dimethoxyphenyl)-3-methyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester | HCID 10180682 | — |
Reaktionsschritte
Compound 46 was prepared by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 1,2-dimethoxy-4-prop-1-enylbenzene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06699877B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-41d411c9f7f148f097b128270da8a730 |
| Quellennotiz | uspto-grants-2004_03 |