HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2-(4-(Trifluoromethyl)phenyl)thiazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Acetaldehyde, bromo- | HCID 105131 | — |
| Edukt | 4-(Trifluoromethyl)thiobenzamide | HCID 2734823 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-(4-(Trifluoromethyl)phenyl)thiazole | HCID 14601969 | 49,3% |
Reaktionsschritte
In a manner similar to Step B of Example 1, the reaction of 10.0 grams (0.0487 mole) of (4-trifluoromethylphenyl)thiocarboxamide, 125 ml of ethanol, 8.35 grams (0.0490 mole) of bromoacetaldehyde, and 2 ml of concentrated hydrochloric acid produced 5.5 grams of 2-(4-trifluoromethylphenyl)thiazole as a solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04889867 |
| Quelldatensatz | uspto-grants-1989_12 |
| ORD ID | ord-b34f6ddb17ac42a98ce05c0042e80386 |
| Quellennotiz | uspto-grants-1989_12 |