HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 478629Erstellt: 24. Oktober 2026
Acetone → 4-(4-(Propan-2-yl)piperazin-1-yl)benzoic acid hydrochloride
https://huagongshe.com/de/reaction/478629
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Acetone | HCID 180 | — |
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Methyl 4-(4-propan-2-yl-piperazin-1-yl)benzoate | HCID 69129778 | — |
| Produkt | 4-(4-(Propan-2-yl)piperazin-1-yl)benzoic acid hydrochloride | HCID 47002203 | — |
Reaktionsschritte
4-(4-Isopropyl-piperazin-1-yl)-benzoic acid methyl ester (0.9 mmol) is dissolved in 4N HCl (2 ml) and heated under reflux for 7 hours. The mixture is cooled in an ice bath to 0-4° C. and acetone is added. The solid material formed is filtered off, washed with cold acetone and dried (vacuum). A pale-brown powder with mp. >270° C., Rf=0.08 (CH2Cl2/MeOH=9:1) is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US06642239B2 |
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| Quelldatensatz | uspto-grants-2003_11 |
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| ORD ID | ord-cfc40f076cc64d3a88489e8e7a488252 |
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| Quellennotiz | uspto-grants-2003_11 |
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