HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Chloroacetyl chloride → 2-Chloro-1-[4-(2-cyanophenyl)piperazin-1-yl]ethanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Chloroacetyl chloride | HCID 6577 | — |
| Edukt | Calcium Carbonate | HCID 10112 | — |
| Edukt | N-(2-Cyanophenyl)piperazine | HCID 2735875 | — |
| Edukt | 2-Chloro-1-(4-o-tolylpiperazin-1-yl)ethanone | HCID 4741212 | — |
| Lösungsmittel | Methyl Ethyl Ketone | HCID 6569 | — |
| Produkt | 2-Chloro-1-[4-(2-cyanophenyl)piperazin-1-yl]ethanone | HCID 10400554 | — |
Reaktionsschritte
Compound 17A is prepared according to the same procedure as that for 12A, using the following reactants: chloroacetyl chloride (670 μl, 8.4 mmol), 1-(2-cyanophenyl)piperazine (1.32 g, 7 mmol), calcium carbonate (2.1 g, 21 mmol), methyl ethyl ketone (30 ml).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05789412 |
| Quelldatensatz | uspto-grants-1998_08 |
| ORD ID | ord-ba90fcc583e242a0a902eaec2bc6b1ed |
| Quellennotiz | uspto-grants-1998_08 |