HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Fluorophenylboronic acid → Emd-50929
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Edukt | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| Edukt | Methyl 5-(4-fluorophenyl)nicotinate | HCID 22743456 | — |
| Produkt | Emd-50929 | HCID 11378949 | — |
Reaktionsschritte
15.3 g of methyl 5-(4-fluorophenyl)nicotinate (obtainable by Suzuki coupling of methyl 5-bromopyridine-3-carboxylate with 4-fluorobenzeneboronic acid analogously to Example 1 or 2) are saponified by conventional methods to give 5-(4-fluorophenyl)nicotinic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06703509B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-cd26b86a68d2414683332086861e6679 |
| Quellennotiz | uspto-grants-2004_03 |