4-[Bis(4-fluorophenyl)methylene]-1-(phenylmethyl)piperidine → 4-(Bis(4-fluorophenyl)methylene)piperidine

Beteiligte Stoffe

Reaktionsschritte

A mixture of 1.6 parts of 4-[bis(4-fluorophenyl)methylene]-1-(phenylmethyl)piperidine and 80 parts of methanol was hydrogenated at normal pressure and at room temperature with 1 part of rhodium-on-charcoal catalyst 5%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off and the filtrate was evaporated, yielding 1.2 parts of 4-[bis(4-fluorophenyl)methylene]piperidine as a residue (intermediate 14).

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