HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Hydroxypropionic acid → beta-Carboxyethyl 10,11-Dihydro-11-oxodibenzo[b,f]thiepin-3-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Hydroxypropionic acid | HCID 68152 | — |
| Edukt | Sodium | HCID 5360545 | — |
| Edukt | 3-Chlorocarbonyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin | HCID 20270211 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | beta-Carboxyethyl 10,11-Dihydro-11-oxodibenzo[b,f]thiepin-3-carboxylate | HCID 20270225 | — |
Reaktionsschritte
Dissolve 1.0 gm. of 3-chlorocarbonyl-10,11-dihydro-11-oxodibenzo[b,f]thiepin in 20 cc. of tetrahydrofuran and add 1.0 gm. of the sodium salt of β-hydroxypropionic acid. Stir the mixture at room temperature for 18 hours. Filter and evaporate the filtrate to dryness. Recrystallize the solid residue from ethanol to obtain the title product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04536507 |
| Quelldatensatz | uspto-grants-1985_08 |
| ORD ID | ord-8905073b85194a5088311a6580caff38 |
| Quellennotiz | uspto-grants-1985_08 |