HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 49063Erstellt: 24. Oktober 2026
Piperidine → 3-[5-(3-Diethylamino-propyl)-1H-indol-2-ylmethylene]-5-phenyl-1,3-dihydro-indol-2-one
https://huagongshe.com/de/reaction/49063
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | 5-Phenyloxindole | HCID 13301978 | — |
| Edukt | 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde | HCID 22042114 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 3-[5-(3-Diethylamino-propyl)-1H-indol-2-ylmethylene]-5-phenyl-1,3-dihydro-indol-2-one | HCID 69586695 | 11,7% |
Reaktionsschritte
A mixture of 5-phenyl-2-oxindole (41 mg, 0.19 mmol), 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde (50 mg, 0.19 mmol) and piperidine(0.1 mL) in ethanol (1 mL) was heated in a sealed tube at 95° C. for 20 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 10 mg (11 %) of the title compound as an orange crystalline solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US06706709B2 |
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| Quelldatensatz | uspto-grants-2004_03 |
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| ORD ID | ord-05f3cb6007a04a2b9ea99cc0e1dd307b |
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| Quellennotiz | uspto-grants-2004_03 |
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