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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 49063Erstellt: 24. Oktober 2026

Piperidine → 3-[5-(3-Diethylamino-propyl)-1H-indol-2-ylmethylene]-5-phenyl-1,3-dihydro-indol-2-one

https://huagongshe.com/de/reaction/49063

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPiperidineHCID 8082—
Edukt5-PhenyloxindoleHCID 13301978—
Edukt5-(3-diethylamino-propyl)-1H-indole-2-carbaldehydeHCID 22042114—
LösungsmittelEthanolHCID 702—
Produkt3-[5-(3-Diethylamino-propyl)-1H-indol-2-ylmethylene]-5-phenyl-1,3-dihydro-indol-2-oneHCID 6958669511,7%

Reaktionsbedingungen

Temperatur95 °C

Reaktionsschritte

A mixture of 5-phenyl-2-oxindole (41 mg, 0.19 mmol), 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde (50 mg, 0.19 mmol) and piperidine(0.1 mL) in ethanol (1 mL) was heated in a sealed tube at 95° C. for 20 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 10 mg (11 %) of the title compound as an orange crystalline solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06706709B2
Quelldatensatzuspto-grants-2004_03
ORD IDord-05f3cb6007a04a2b9ea99cc0e1dd307b
Quellennotizuspto-grants-2004_03