HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethyl Ether → N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethyl Ether | HCID 3283 | — |
| Edukt | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| Edukt | Benzyl (cis)-2-[(2-{[4-(aminosulfonyl)benzoyl]amino)cyclohexyl)amino]-2-oxoethylcarbamate | HCID 86587037 | — |
| Produkt | N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide | HCID 68830145 | — |
Reaktionsschritte
The material from above benzyl (cis)-2-[(2-{[4-(aminosulfonyl)benzoyl]amino}cyclohexyl)amino]-2-oxoethylcarbamate (217 mg) was dissolved in 30% HBr/AcOH (5 mL) at rt. After 1 h, Et2O was added and the solid was collected to give N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide. MS found: (M+H)+=355.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06706712B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-f954d0b4badc4c8c9d0a3a32d1b865ff |
| Quellennotiz | uspto-grants-2004_03 |