Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Benzoyl chloride | HCID 7412 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Carbamimidic acid, methyl ester, sulfate (1:1) | HCID 169039 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | HCID 69749939 | HCID 69749939 | — |
Reaktionsschritte
O-Methylisourea hydrogen sulfate (17.2 g, 0.1 mol) was suspended in water (100 mL) containing NaOH (20 g, 0.5 mol) and the mixture cooled to 5-10° C. The mixture was stirred vigorously as benzoyl chloride (35.15 g, 0.25 mol) was added at such a rate that the reaction temperature did not rise above 15° C. After the last addition, the mixture was stirred for 3 h and the resulting solid collected by vacuum filtration to give N,N′-dibenzoylcarbamimidoic acid, methyl ester.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06946554B2 |
|---|
| Quelldatensatz | uspto-grants-2005_09 |
|---|
| ORD ID | ord-cb9abf06b9da49438ab90561af0414ed |
|---|
| Quellennotiz | uspto-grants-2005_09 |
|---|
