HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → {2-[3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-4-trifluoromethyl-5-vinyl-phenyl}-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester | HCID 11266473 | — |
| Edukt | Carbamic acid,[2-amino-5-ethenyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester | HCID 69486994 | — |
| Produkt | {2-[3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-4-trifluoromethyl-5-vinyl-phenyl}-carbamic acid tert-butyl ester | HCID 86589378 | — |
Reaktionsschritte
The title compound was prepared from (2-amino-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl ester (Example J34) (227 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as a yellow oil (290 mg, 60%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06949542B2 |
| Quelldatensatz | uspto-grants-2005_09 |
| ORD ID | ord-35a565c253294dfea688e63ceacffe54 |
| Quellennotiz | uspto-grants-2005_09 |