HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Fluoro-4-methoxybenzoyl chloride → N3-(3-Fluoro-4-methoxybenzoyl)-N2-[1-(4-pyridyl)piperidin-4-ylmethyl)-2,3-pyridinediamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Fluoro-4-methoxybenzoyl chloride | HCID 2779255 | — |
| Edukt | N2-[1-(4-pyridyl)piperidin-4-ylmethyl]-2,3-pyridinediamine | HCID 12150690 | — |
| Produkt | N3-(3-Fluoro-4-methoxybenzoyl)-N2-[1-(4-pyridyl)piperidin-4-ylmethyl)-2,3-pyridinediamine | HCID 9932680 | 25,6% |
Reaktionsschritte
Using a similar procedure to that described in Example 2, Part D, N2-[1-(4-pyridyl)piperidin-4-ylmethyl]-2,3-pyridinediamine (300 mg, 1.06 mmol) and 3-fluoro-4-methoxybenzoyl chloride (200 mg, 1.17 mmol) yielded 118 mg (15%) of the title compound as a hydrochloride salt.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06710057B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-eae5efb3fc024760918dd224223ab3cd |
| Quellennotiz | uspto-grants-2004_03 |