HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanol → Methyl 3-thienylacetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanol | HCID 887 | — |
| Edukt | 3-Thiophenacetic acid | HCID 23404 | — |
| Produkt | Methyl 3-thienylacetate | HCID 94041 | — |
Reaktionsschritte
To 2-(thiophen-3-yl)acetic acid in MeOH at 0° C. was added TMS-CH2N2. The solution was stirred for 3 hours then quenched with a few drops of AcOH. The solvents were evaporated. Column chromatography (SiO2, 3-15% EtOAc/Hex) gave pure methyl 2-(thiophen-3-yl)acetate (E41).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09096569B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-a19af21a912d4b2f89b4a2c300d895d3 |
| Quellennotiz | uspto-grants-2015_08 |