HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate → tert-Butyl 4-(3-aminophenyl)piperazine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate | HCID 22330126 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | tert-Butyl 4-(3-aminophenyl)piperazine-1-carboxylate | HCID 22330182 | — |
Reaktionsschritte
To a solution of tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate in EtOH (20 mL) and THF (10 mL) was added Pd/C (500 mg), the mixture was charged with H2 (1 atm) and stirred for 16 h. Pd/C was filtered off, the filtrate was concentrated to give tert-butyl 4-(3-aminophenyl)piperazine-1-carboxylate (1.71 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09102625B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-1ed4b68bf7e8475f86a60a9f5e6fa90a |
| Quellennotiz | uspto-grants-2015_08 |