8-Aminoquinoline-7-carboxaldehyde → 1-(8-Amino-quinolin-7-yl)-propan-1-ol

Beteiligte Stoffe

Reaktionsschritte

In a similar fashion using route 27 general procedure 66, 8-amino-quinoline-7-carbaldehyde 404 (1 g, 5.83 mmol), ethyl magnesium bromide (3M in THF; 5.81 ml, 17.44 mmol) and THF (30 ml) gave the title compound (900 mg, 91%) after purification by column chromatography with DCM/MeOH (99:1) as the eluent.

Herkunft & Nachweise