Thionyl Chloride → 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride

Beteiligte Stoffe

Reaktionsschritte

4′-Trifluoromethyl-biphenyl-2-carboxylic acid (25 g, 94 mmol) was combined with thionyl chloride (35 ml, 470 mmol) and the mixture was heated at reflux. After 2 h, the mixture was concentrated under vacuum to afford 26.5 g of the title product as a light yellow oil.

Herkunft & Nachweise