HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2,4-Diaminoquinazoline-6-carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Potassium Cyanide | HCID 9032 | — |
| Edukt | 2,4,6-Triaminoquinazoline | HCID 292661 | — |
| Edukt | Sodium Nitrite | HCID 23668193 | — |
| Katalysator | Copper sulfate pentahydrate | HCID 24463 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 2,4-Diaminoquinazoline-6-carbonitrile | HCID 282699 | — |
Reaktionsschritte
The 2,4,6-triaminoquinazoline derivatives described above may then optionally be treated with 2N hydrochloric acid, sodium nitrite, potassium cyanide, and copper(II) sulfate pentahydrate in water, affording the corresponding 2,4-diamino-6-cyanoquinazoline, for example, 2,4-diamino-6-cyano-5-methylquinazoline. Step A of Example 14 describes in detail this step in the reaction sequence.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05616718 |
| Quelldatensatz | uspto-grants-1997_04 |
| ORD ID | ord-7093a7fae48f41c8aee7b43ad15a91f4 |
| Quellennotiz | uspto-grants-1997_04 |