HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2-(Pyrimidin-4-yl)benzoic acid hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Methyl 2-(pyrimidin-4-yl)benzoate | HCID 86680852 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 2-(Pyrimidin-4-yl)benzoic acid hydrochloride | HCID 86680853 | — |
Reaktionsschritte
A mixture of methyl 2-(pyrimidin-4-yl)benzoate (0.49 g), acetic acid (2.0 mL) and 6 N hydrochloric acid (10 mL) was heated under reflux for 5 hr. The solvent was evaporated under reduced pressure, and the obtained residue was washed with ethyl acetate to give the title compound (0.45 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08865717B2 |
| Quelldatensatz | uspto-grants-2014_10 |
| ORD ID | ord-93ddf8e9b2694f25803e12a7d3ebd9ae |
| Quellennotiz | uspto-grants-2014_10 |