Ethyl formate → Benzyl [3-(formylamino)propyl]carbamate

Beteiligte Stoffe

Reaktionsschritte

Benzyl 3-aminopropylcarbamate 12 (8.00 g, 36.0 mmol) was dissolved in 250 mL of ethyl formate. The solution was refluxed for 4 h. Following complete conversion of the amine, the solution was concentrated to dryness in a rotary evaporator to obtain the formamide as a colorless oil (8.90 g, 99%).

Herkunft & Nachweise