Hydrochloric Acid → 2-(Pyrimidin-4-yl)benzoic acid hydrochloride

Beteiligte Stoffe

Reaktionsschritte

A mixture of methyl 2-(pyrimidin-4-yl)benzoate (0.49 g), acetic acid (2.0 mL) and 6 N hydrochloric acid (10 mL) was heated under reflux for 5 hr. The solvent was evaporated under reduced pressure, and the obtained residue was washed with ethyl acetate to give the title compound (0.45 g).

Herkunft & Nachweise