HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Imidazole → HCID 19959422, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Imidazole | HCID 795 | — |
| Edukt | 2-Bromo-1-(5-chloropyridin-2-yl)ethan-1-one hydrobromide | HCID 19959414 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | HCID 19959422 | HCID 19959422 | — |
Reaktionsschritte
15 g of 2-bromoacetyl-5-chloropyridine hydrobromide are dissolved in 50 ml of dry dichloromethane, 9.7 g of imidazole are added and the mixture is stirred for 24 hours at room temperature. Evaporation of the solvent in vacuo and subsequent chromatography of the residue over silicagel (dichloromethane/methanol/heptane=7/1/4) yield the compound as a cream coloured solid; m.p.: 122°-129°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05622982 |
| Quelldatensatz | uspto-grants-1997_04 |
| ORD ID | ord-d144c05ae6ae4a7bbc14d81edc48c273 |
| Quellennotiz | uspto-grants-1997_04 |