HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 54545Erstellt: 24. Oktober 2026
Water → N-[2-[1-tert-butoxycarbonylpiperidin-4-yl]ethyl]phthalimide
https://huagongshe.com/de/reaction/54545
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Water | HCID 962 | — |
| Edukt | tert-Butyl 4-(2-((methanesulfonyl)oxy)ethyl)piperidine-1-carboxylate | HCID 15229596 | — |
| Edukt | Phthalimide potassium salt | HCID 24194345 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | N-[2-[1-tert-butoxycarbonylpiperidin-4-yl]ethyl]phthalimide | HCID 15851771 | 80% |
Reaktionsschritte
A mixture of 1-tert-butoxycarbonyl-4-(2-mesyloxyethyl)piperidine (1.20 g) and potassium phthalimide (0.80 g) in N,N-dimethylformamide (15 ml) was stirred at 40° C. for 2 hours. The mixture was poured into water and extracted with ethyl acetate. The extract was washed with water, and dried over magnesium sulfate and evaporated in vacuo to give N-[2-[1-tert-butoxycarbonylpiperidin-4-yl]ethyl]phthalimide (1.12 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US05622976 |
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| Quelldatensatz | uspto-grants-1997_04 |
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| ORD ID | ord-834af114af9340198c258f1eb7345cf9 |
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| Quellennotiz | uspto-grants-1997_04 |
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