HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 54825Erstellt: 24. Oktober 2026
Lithium azide → 1,4-Anhydro-5-azido-5-deoxy-2-S-[(4-methoxyphenyl)-methyl]-2-thio-L-arabinitol
https://huagongshe.com/de/reaction/54825
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Lithium azide | HCID 88163 | — |
| Edukt | 1,4-Anhydro-2-S-[(4-methoxyphenyl)methyl]-2-thio-L-arabinitol 5-(4-Methylbenzenesulfonate) | HCID 88337105 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1,4-Anhydro-5-azido-5-deoxy-2-S-[(4-methoxyphenyl)-methyl]-2-thio-L-arabinitol | HCID 131719993 | 32,6% |
Reaktionsschritte
A mixture of 2.0 g of product from Example 324, 0.460 g of lithium azide and 2 ml of N,N-dimethylformamide is stirred at 70° C. for 65 hours. The reaction mixture is concentrated in vacuo. The residue is purified by chromatography (Silica gel: 30% ethyl acetate/hexane) to give 0.454 g of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US05623081 |
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| Quelldatensatz | uspto-grants-1997_04 |
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| ORD ID | ord-5061bb5743e04cedafaf182a0c9038b8 |
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| Quellennotiz | uspto-grants-1997_04 |
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