HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Dichlorobenzylamine → Gsk1370319A
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Dichlorobenzylamine | HCID 1485 | — |
| Edukt | (4-Fluoro-2-(trifluoromethyl)phenyl)methanamine | HCID 2734878 | — |
| Edukt | N-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxoprolinamide | HCID 67458706 | — |
| Produkt | Gsk1370319A | HCID 67461788 | — |
Reaktionsschritte
N-[(2,4-dichlorophenyl)methyl]-1-methyl-5-oxoprolinamide was prepared in a manner analogous to that described above for the synthesis of N-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxoprolinamide (Example 83) but [(2,4-dichlorophenyl)methyl]amine was substituted for {[4-fluoro-2-(trifluoromethyl)phenyl]methyl}amine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08048907B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-dea8d8dbf8a446459a5e322827833688 |
| Quellennotiz | uspto-grants-2011_11 |