HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Fluorophenylboronic acid → HCID 10292840, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Fluorophenylboronic acid | HCID 2734354 | — |
| Edukt | 4-Chloro-6-((2,6-difluorophenyl)amino)-2-(methylthio)pyrimidine-5-carbaldehyde | HCID 9944737 | — |
| Produkt | HCID 10292840 | HCID 10292840 | — |
Reaktionsschritte
Prepared as described above in Example 11 starting from 4-chloro-6-(2,6-difluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde and 2-fluorophenylboronic acid to give the title compound 4-(2,6-difluoro-phenylamino)-6-(2-fluoro-phenyl)-2-methylsulfanyl-pyrimidine-5-carbaldehyde. 1H-NMR: δ0.31 (s, 3H), 6.98-7.20 (m, 3H), 7.26 (m, 2H), 7.38-7.42 (m, 2H), 9.79 (s, 1H), 10.39 (br s, 1H). LC MS (m/e)=376 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08058282B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-0f3e71333f0b4894836f896501939f00 |
| Quellennotiz | uspto-grants-2011_11 |