HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methyl-3-(trifluoromethyl)benzoic acid → 4-Methyl-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-3-trifluoromethyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methyl-3-(trifluoromethyl)benzoic acid | HCID 2775592 | — |
| Edukt | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone | HCID 66998654 | — |
| Produkt | 4-Methyl-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-3-trifluoromethyl-benzamide | HCID 66998783 | — |
Reaktionsschritte
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 4-Methyl-3-trifluoromethyl-benzoic acid. LC-MS (basic): tR=1.00 min; [M+H]+=514.1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08063099B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-51b68cfb8a84454e86779f7d31a818fa |
| Quellennotiz | uspto-grants-2011_11 |