HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Bromo-1-[4-(hydroxymethyl)phenyl]ethanone → 4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Bromo-1-[4-(hydroxymethyl)phenyl]ethanone | HCID 19798053 | — |
| Edukt | 4-(4-Fluorobenzyloxy)-1h-pyridin-2-one | HCID 22049900 | — |
| Edukt | 4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006842 | — |
| Produkt | 4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 58042834 | — |
Reaktionsschritte
4-(4-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one is prepared following preparation 15b (DMSO as solvent) from 1.10 g (5.00 mmol) 4-(4-fluoro-benzyloxy)-1H-pyridin-2-one (preparation 22.1) and 1.15 g (5.00 mmol) 2-bromo-1-(4-hydroxymethylphenyl)-ethanone (preparation 15a).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08067590B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-c43f0f57e6dd4d829e5d41df5c72b4e9 |
| Quellennotiz | uspto-grants-2011_11 |