HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzoic acid, 4-amino-, 1,1-dimethylethyl ester → tert-Butyl 4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)benzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzoic acid, 4-amino-, 1,1-dimethylethyl ester | HCID 233272 | — |
| Edukt | 2-[4-(5-Chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid | HCID 117622850 | — |
| Produkt | tert-Butyl 4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)benzoate | HCID 117622812 | — |
Reaktionsschritte
76 mg (purity 83%, 0.21 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) and 1.1 eq. of tert-butyl 4-aminobenzoate were reacted according to General Method 5A. Yield: 43 mg (43% of theory)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09434690B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-72419dfbf9d143289dac1c8fc15eaf2b |
| Quellennotiz | uspto-grants-2016_09 |