Sodium borohydride → 4-Hydroxymethyl-5-(3-methoxyphenyl)-1-phenylpyrrolidin-2-one

Beteiligte Stoffe

Reaktionsschritte

To 26.7 gm. of methyl 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylate in 200 ml of absolute methanol was added slowly at 0°-10°24.8 gm. of sodium borohydride. The reaction was run and worked up following the procedure of example 1D. Drying (Na2SO4), filtration, and concentration in vacuo provided 17.2 gm. of colorless crystals, m.p. 123°-126°.

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