4-(3-(Trifluoromethyl)Phenyl)Piperidine → 9-[1-(3,4-Dimethoxybenzoyl)-2-[5-[4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]pentyl]-1,2,3,4-tetrahydro-4-quinolinyl]-9H-carbazole

Beteiligte Stoffe

Reaktionsschritte

Starting with 5-[4-(9H-9-carbazolyl)-1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydro-2-quinolinyl]-1-pentanol (0.19 g, 0.32 mmol) prepared in Example 135 and 4-[3-(trifluoromethyl)phenyl]piperidine (0.23 g, 1 mmol), the same procedure as shown in Example 136 was repeated to give the titled compound (0.13 g, yield: 53%) as a white crystal (cis:trans=3:1).

Herkunft & Nachweise