HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
O-Toluidine → 1-(2-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | O-Toluidine | HCID 7242 | — |
| Edukt | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(2-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid | HCID 4405457 | 91% |
Reaktionsschritte
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g, 1.47 mmol) and o-toluidine (0.470 mL; 4.41 mmol) in ethanol (3 mL). 2-oxo-1-o-tolylpyrrolidine-3-carboxylic acid 0.292 g (91%) was obtained as a white film.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09434722B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-53d1152f05f74e8bad11f9b10c4d6e93 |
| Quellennotiz | uspto-grants-2016_09 |