HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 586399Erstellt: 24. Oktober 2026
1-Fluoro-3-nitrobenzene → 1-Methyl-4-(3-nitrophenyl)piperazine
https://huagongshe.com/de/reaction/586399
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 1-Fluoro-3-nitrobenzene | HCID 9823 | — |
| Edukt | 1-Methylpiperazine | HCID 53167 | — |
| Produkt | 1-Methyl-4-(3-nitrophenyl)piperazine | HCID 12152161 | — |
Reaktionsschritte
A mixture of 3-fluoronitrobenzene (20 ml; 0.19 mol) and 1-methylpiperazine (40 ml; 0.36 mol) was heated to 120° C. for a week. The cooled mixture was purified by column-chromatography on silica gel using a mixture of ethyl acetate and methanol (9:1 v/1) as the eluent. Yield: 33 g (79%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US06936613B2 |
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| Quelldatensatz | uspto-grants-2005_08 |
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| ORD ID | ord-ee474b006a704546bf9351a9bd8a51d2 |
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| Quellennotiz | uspto-grants-2005_08 |
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