HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-methyl-1H-indole-5-carbaldehyde → 5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-methyl-1H-indol-5-yl)methyl)pyrrolidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-methyl-1H-indole-5-carbaldehyde | HCID 7537534 | — |
| Edukt | Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate | HCID 69085588 | — |
| Produkt | 5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-methyl-1H-indol-5-yl)methyl)pyrrolidin-2-one | HCID 69084514 | — |
Reaktionsschritte
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with commercially available 1-methyl-1H-indole-5-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.84 min.; [M+H]+: 378.93 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-afd129c27ea94903b2d9002c22c5399c |
| Quellennotiz | uspto-grants-2016_01 |