Dimethylamine → N,N-dimethyl-6-nitropyridin-3-amine

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of 1 g of 5-bromo-2-nitropyridine in 5 mL of ethanol are added 6 mL of a 2 M solution of dimethylamine in tetrahydrofuran. The reaction mixture is heated for 2 hours at 140° C. in a microwave machine. After cooling, the solid formed is separated off and washed with ethyl ether to give 850 mg of N,N-dimethyl-6-nitropyridine-3-amine in the form of a yellow solid.

Herkunft & Nachweise