HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → Pentafluorobenzenesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Ammonium Chloride | HCID 25517 | — |
| Edukt | 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride | HCID 70026 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Produkt | Pentafluorobenzenesulfonamide | HCID 2063927 | 36% |
Reaktionsschritte
Under room temperature, a solution of 468 g of pentafluorobenzenesulfonyl chloride in acetone was added dropwise to an aqueous solution containing 964 g of ammonium chloride, during which a pH was adjusted to 7 with an aqueous sodium hydroxide solution. The precipitated product was filtered, and recrystallized from toluene to obtain 156 g of pentafluorobenzenesulfonamide as white crystals. A structure was confirmed by 1H-NMR, 19F-NMR and IR.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07910686B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-9e29f437fa32492cbe862a61782d3444 |
| Quellennotiz | uspto-grants-2011_03 |