HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 606240Erstellt: 24. Oktober 2026
4-(Phenoxymethyl)piperidine → 2-Tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine
https://huagongshe.com/de/reaction/606240
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 4-(Phenoxymethyl)piperidine | HCID 3017444 | — |
| Edukt | 2-Tert-butoxy-6-vinylpyrazine | HCID 22248276 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-Tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine | HCID 22248528 | — |
Reaktionsschritte
After dissolving 471 mg of 2-tert-butoxy-6-vinylpyrazine and 505 mg of 4-(phenoxymethyl)piperidine in 10 ml of ethanol, the mixture was stirred for 4 days at 80° C. The reaction solution was concentrated under reduced pressure and the residue was purified by NH silica gel column chromatography (solvent: n-hexane/ethyl acetate) to obtain 2-tert-butoxy-6-[2-(4-phenoxymethylpiperidino)ethyl]pyrazine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07915274B2 |
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| Quelldatensatz | uspto-grants-2011_03 |
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| ORD ID | ord-9e16f06448fc4f8fb6369ece4d7ea4d2 |
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| Quellennotiz | uspto-grants-2011_03 |
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