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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 606484Erstellt: 24. Oktober 2026

Diethyl Oxalate → Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate

https://huagongshe.com/de/reaction/606484

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDiethyl OxalateHCID 7268—
Edukt2-Amino-5-chlorobenzamideHCID 78876—
ProduktEthyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylateHCID 13581026258%

Reaktionsschritte

2-Amino-5-chlorobenzamide (2.387 g) and diethyl oxalate were stirred at 175° C. for 6 hr. The mixture was allowed to cool, and the obtained crude crystals were washed with hot ethanol to give the title compound (2.051 g, 58%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07915267B2
Quelldatensatzuspto-grants-2011_03
ORD IDord-35afc13731924c5e8c288c675a8e5e50
Quellennotizuspto-grants-2011_03