HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethyl Oxalate → Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethyl Oxalate | HCID 7268 | — |
| Edukt | 2-Amino-5-chlorobenzamide | HCID 78876 | — |
| Produkt | Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate | HCID 135810262 | 58% |
Reaktionsschritte
2-Amino-5-chlorobenzamide (2.387 g) and diethyl oxalate were stirred at 175° C. for 6 hr. The mixture was allowed to cool, and the obtained crude crystals were washed with hot ethanol to give the title compound (2.051 g, 58%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915267B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-35afc13731924c5e8c288c675a8e5e50 |
| Quellennotiz | uspto-grants-2011_03 |