HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Benzoxazolinone, 5-bromo- → (S)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]-5-[(2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)ethynyl]nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Benzoxazolinone, 5-bromo- | HCID 26853 | — |
| Edukt | (S)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]-5-[(trimethylsilyl)ethynyl]nicotinamide | HCID 24953135 | — |
| Produkt | (S)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]-5-[(2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)ethynyl]nicotinamide | HCID 24954922 | 40,5% |
Reaktionsschritte
In a manner similar to that described in Example 443, (S)-N-[methyl(oxo)phenyl-λ6-sulfanylidene]-5-[(trimethylsilyl)ethynyl]nicotinamide (150 mg, 0.42 mmol) and 5-bromo-2-benzoxazolinone (102 mg, 0.46 mmol) were reacted to give the title compound as light yellow solid (71 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915443B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-aa1bf181dbf94cfd8c8858349a944f09 |
| Quellennotiz | uspto-grants-2011_03 |