HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Methylamino)propane-1,2-diol → N-[{3-[(2,3-dihydroxypropyl)(methyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Methylamino)propane-1,2-diol | HCID 2734122 | — |
| Edukt | N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585264 | — |
| Produkt | N-[{3-[(2,3-dihydroxypropyl)(methyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585224 | — |
Reaktionsschritte
In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and 3-methylamino-1,2-propanediol were converted to the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915443B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-51f9e9b8266c43e494d304aa85b158cc |
| Quellennotiz | uspto-grants-2011_03 |