HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thiomorpholine 1,1-dioxide → (S)-N-{[3-(1,1-dioxidothiomorpholin-4-yl)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thiomorpholine 1,1-dioxide | HCID 6484228 | — |
| Edukt | N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 76585264 | — |
| Produkt | (S)-N-{[3-(1,1-dioxidothiomorpholin-4-yl)propyl](oxido)phenyl--sulfanylidene}-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide | HCID 57657888 | — |
Reaktionsschritte
In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and thiomorpholine-1,1-dioxide were converted to the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915443B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-99f8ef1589184e79bd08e12e9a53808f |
| Quellennotiz | uspto-grants-2011_03 |