Enprofylline → HCID 14014540, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A suspension of 9.32 g. (48 mM) of 3-propylxanthine in 80 ml. of pyridine, was treated with 17.33 g. (78 mM.) of phosphorus pentasulfide in 80 ml. of pyridine, and worked up analogously to Example I. 8.9 g. of 3-propyl-6-thioxanthine was obtained. Recyrstallization from methanol-acetone gave 7.4 g. (59% yield) of needles with a melting point of 249°-250° C.

Herkunft & Nachweise