2-Propanethiol → 6-Isopropylsulfanyl-pyridine-2-carboxylic acid methyl ester

Beteiligte Stoffe

Reaktionsschritte

6-Bromo-pyridine-2-carboxylic acid methyl ester (0.15 g, 0.69 mmol) was added with DMF (2.3 mL), Cs2CO3(0.45 g, 1.38 mmol) and 2-propanethiol (0.064 mL, 0.69 mmol) in turn, and the mixture was stirred at room temperature for 18 hours. After the termination of the reaction, the reactant was filtered and concentrated under reduced pressure to obtain the title compound (0.13 g, 88%).

Herkunft & Nachweise