HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Fluoroaniline → 2-chloro-5-ethyl-N-(4-fluorophenyl)-6-methylpyrimidin-4-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Fluoroaniline | HCID 9731 | — |
| Edukt | 2,4-Dichloro-5,6-dimethylpyrimidine | HCID 241553 | — |
| Edukt | 2-chloro-N-cyclohexyl-5,6-dimethylpyrimidin-4-amine | HCID 82460626 | — |
| Edukt | 2,4-Dichloro-5-ethyl-6-methylpyrimidine | HCID 89761070 | — |
| Produkt | 2-chloro-5-ethyl-N-(4-fluorophenyl)-6-methylpyrimidin-4-amine | HCID 117817658 | — |
Reaktionsschritte
The titled compound was synthesized according to the procedure described for preparation of 2-chloro-N-cyclohexyl-5,6-dimethylpyrimidin-4-amine (Example 1, Step D) using 2,4-dichloro-5-ethyl-6-methylpyrimidine instead 2,4-dichloro-5,6-dimethylpyrimidine and 4-fluoroaniline instead of cyclohexylamine. The titled compound was obtained as a white solid. MS (ESI) m/z 266.7, 268.7 (M+1)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09447051B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-7d6665336df9400aabbf57fe305a1b62 |
| Quellennotiz | uspto-grants-2016_09 |