HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Leucinamide → (S)-5-Cyclopropyl-N-(4-methyl-1-(methylamino)-1-oxopentan-2-yl)-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Leucinamide | HCID 69640 | — |
| Edukt | 5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087254 | — |
| Edukt | 5-Cyclopropyl-6-(tetrahydro-pyran-4-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087560 | — |
| Produkt | (S)-5-Cyclopropyl-N-(4-methyl-1-(methylamino)-1-oxopentan-2-yl)-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamide | HCID 71087765 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(tetrahydro-pyran-4-ylmethoxy)-pyridine-2-carboxylic acid (which can e.g. be prepared in a similar manner than 5-cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 166 b)) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=404.2 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321727B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-7365f5f7331644c5be27af9518a3219c |
| Quellennotiz | uspto-grants-2016_04 |